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UID:e838f14f-10fa-4c28-bd8c-3ae724ce8d30
DTSTAMP:20261110T162014Z
SUMMARY:Development of flexible neural interfaces based on reduced graphene
  oxide brain electrodes with increased long-term stability
DESCRIPTION:<p><strong>IN-PERSON EVENT</strong></p><p><strong>PhD: Georgios
  Alexandros Katirtsidis</strong></p><p><strong>Directors:</strong></p><p>I
 CREA Prof. Jose Antonio Garrido &amp\; Dr Eduard Masvidal</p><p>Graphene-b
 ased thin-film technology offers great potential for next-generation neura
 l interfaces\, but long-term reliability remains challenging due to encaps
 ulation instability in physiological environments. This study presents a h
 ybrid polyimide (PI)/ALD-Al₂O₃ encapsulation integrated with nanoporou
 s reduced graphene oxide (rGO) microelectrodes. The encapsulation demonstr
 ated excellent stability after accelerated aging equivalent to approximate
 ly 2.5 years in phosphate-buffered saline (PBS) at 57 °C and thousands of
  bending cycles.</p><p>Nanoporous rGO microelectrodes maintained their str
 uctural integrity and electrochemical performance after 531 days in PBS\, 
 2 billion stimulation pulses\, and repeated mechanical bending. Chronic im
 plantation in rats demonstrated stable bidirectional recording and stimula
 tion for over three months. Furthermore\, acute implantation in a porcine 
 model enabled successful subcortical and epicortical neural recordings. In
 tegration with a magneto-robotic implantation strategy further highlights 
 the potential for minimally invasive applications. These results establish
  a promising platform for chronic neural monitoring and neuromodulation.</
 p><p>REGISTER <a href="https://forms.cloud.microsoft/Pages/ResponsePage.as
 px?id=7y7ItE2bfUi-qg79NXo6WxH4jECG9S9KmyGb2KoqlQpURDkxMzFDMlZBUDdaTkRKUTdS
 SE42VzRVNiQlQCN0PWcu" target="_blank" data-extlink rel="noopener nofollow 
 noreferrer">HERE</a></p><p>&nbsp\;</p>
DTSTART:20261118T090000
DTEND:20261118T110000
LOCATION:ICN2 Seminar Room
CATEGORIES:ICN2 Theses Defence
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