03 December

Small-scale transport phenomena aspects of on-chip metallic nanostructured based biosensing

Tuesday 03 December 2019, 12:00pm

ICN2 Seminar Hall, ICN2 Building, UAB

Prof. Carlos Escobedo, Department of Chemical Engineering, Queen’s University, Canada

Hosted by: CSIC Research Professor Laura Lechuga, NanoBiosensors and Bioanalytical Applications Group Leader at ICN2

Abstract:The microsystems field has been notably advanced in the last two decades by the remarkable progress in materials and fabrication methodologies at micro- and nanoscales. It is now possible to create miniature platforms containing a vast number of tiny components, microvalves, microchannels, microactuators that, acting in symphony, enable advances in different fields including biology and medicine. Microfluidic platforms, for instance, facilitate the manipulation of reagents and analytes, as well as the study of and interaction of individual microorganisms within a single chip. At the nanoscale, metallic nanostructures are capable to produce accurate photonic signals that can be employed for biosensing purposes. This talk will cover our recent efforts on the development of biosensing approaches that exploit the photonic abilities and their use for the rapid, in situ label-free detection and identification of biomarkers of diseases, illegal drugs and terrorism agents. I will discuss aspects of micro- and nanofluidic transport phenomena in the context of the integration of metallic nanostructure based biosensing. Different nanostructures and sensing strategies will be presented, including surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS), detailing the inherent advantages and challenges associated with the fluidic-optical integration.