28 January

Catechol Poly(disulfide)s: a new platform for adhesives in the medical industry

Friday 28 January 2022, 11:00am

ICN2 Seminar Hall, ICN2 Building, UAB - Hybrid Event


PhD: Miguel Moreno

Director: Dr. Daniel Ruiz Molina, Nanostructured Functional Materials Group Leader at ICN2 

Short Abstract: Catechols are widely present in nature taking part on crucial mechanisms. The fascinating properties of catechols in terms of adhesion, redox activity and chelating properties have raised the recent interest in catechol containing polymers for the development of new functional materials, especially for their potential in the biomedical field as adhesives in medical devices and tissue adhesives/sealants.

In the present thesis a new family of catechol poly(disulfide)s is introduced, combining the most interesting features of catechols and disulfides functionalities. The synthesis and polymerization of novel catechol derivatives is optimized looking for a proper modular approach with fine-tuning of the final molecular. Seeking for potential applications, the adhesion on diverse substrates and the use of these materials as tissue adhesive and sealant is evaluated. Furthermore, in vitro and in vivo studies are carried out, as well as the assessment of the feasible degradation on different media, to evaluate the full potential of these novel materials in the biomedical field.