Inorganic Nanoparticles Group

Group Leader: Víctor F. Puntes

News

Bacterial or viral? Accurate diagnosis of infections with a paper-based test

A new immunoassay test to distinguish viral from bacterial infections could help reduce the use of antibiotics and the consequent development of drug-resistant bacteria. This study published in Nanoscale has been carried out by a team of researchers led by Prof. Kimberly Hamad-Schifferli, from the University of Massachusetts, and ICREA prof. Victor F. Puntes, from the ICN2 and the VHIR.





The CONCORD project aims to improve the immunotherapy of Chronic Lymphocytic Leukaemia with gold nanoparticles

Selected by the European Commission through the EuroNanoMed programme, this project aims to improve CAR T cell therapy using messenger RNA (mRNA). Its aim is to make the therapeutic effect more sustained thanks to gold nanoparticles that will control the release of mRNAs. The project is coordinated by the ICN2 and has the experience of Hospital Clínic de Barcelona - IDIBAPS, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri" in Milan and Tel Aviv University in Tel Aviv.


Crazy for Physics launches its fourth edition

25 High School students will interact during 16 work sessions with researchers from all the participating excellence centers offering exciting experiences that explore the biggest and the smallest scales of the universe. Coordinated from the ICN2 and the IFAE, Crazy for Physics (Bojos per la Física) also involves the UAB, the ICMAB, the ICFO and the Alba Synchrotron.


Crazy for Physics 3rd year

The 3rd edition of the Crazy for Physics programme, funded by the Fundació Catalunya / La Pedrera and coordinated by the ICN2 and IFAE, ended at Món Natura Pirineus with a weekend devoted to science and the future perspectives of the participants. Some 25 outstanding high school students enjoyed a year of theoretical and practical experiences at some of the best Catalan research centres.


Nanoscience and the ICN2 star at the CosmoCaixa European Researcher’s Night

The European Researchers’ Night is a Europe-wide effort to boosts public awareness of the positive role of research in society. This year’s program included a series of events at CosmoCaixa, with a specific area devoted to nanoscience and nanotechnology. Many coordinated institutions, including the ICN2, made it possible.



BIST holds its annual conference at CosmoCaixa

BIST Director General says modernising research facilities and providing training to boost the social impact of science are the top priorities of the Barcelona Institute of Science and Technology. The event, held at CosmoCaixa, offers an overview about several transversal research issues being tackled by the BIST institutions.


Nanoscience taken out of the lab at the 10alamenos9 Festival

The 10alamenos9 Festival of Nanoscience and Nanotechnology was held last week, with over 100 activities to choose from across many locations in Spain. Among them, the UAB Campus in Bellaterra, where a lively activity was run for over 200 students, including a visit to the ICN2.


BIST reveals the five Ignite seed projects for 2018

Today the Barcelona Institute of Science and Technology (BIST) announce the five projects that will receive seed funding under the 2018 edition of its Ignite programme to accelerate multidisciplinary research at its member institutes.


ICN2 nanomedicine on the radio

ICREA Prof. Victor Puntes, leader of the ICN2 Inorganic Nanoparticles Group, discussed the latest advances in nanomedicine on regional radio station RAC1. He shared the Via Lliure microphones with Dr. Elena Martínez of IBEC and science journalist Núria Jar.



ICN2 in the Media: Diari Ara reflects on cyborgs and nanorobots

An article in Ara newspaper reflects on what makes a cyborg a cyborg and considers the far-reaching influence that technology has on human beings. ICREA Research Prof. Victor F. Puntes shares his views on how nanorobots and nanoparticles will change the diagnosis and treatment of diseases such as cancer. For him, if humankind were ever to achieve immortality, we would be doomed within five minutes.



Mad for Science: Over 200 students start their first scientific adventure

Mad for Science is a consolidated Program organised by Fundació Catalunya-La Pedrera and devoted to bring High School sudents closer to research. ICN2, IFAE and UAB lead the second edition of Mad for Physics. It is a great opportunity for 25 brilliant young students to have a first contact with real research. The Program offers an overview of different research lines, including the participation of researchers from ICMAB, ICFO and Alba Synchrotron.


Cerium oxide nanoparticles may be of therapeutic value in chronic liver disease

Researchers from clinical and basic research institutes located in Barcelona used Cerium oxide NPs to treat cirrhosis in model rats. In a work published in Journal of Hepatology, they observed how it has dramatic beneficial effects in reducing inflammation and allowing tissue reparation. What makes nanoceria very appealing is its high capacity to buffer electrons from an oxidant/reducing environment, followed by the capture or release of oxygen, or molecular oxygen species which are very reactive oxygen species (ROS).


ICN2 in the Media: Nanotechnology visits El Punt TV

L’Illa de Robison is a TV show broadcasted in the Catalan TV station El Punt Avui TV. The program was recently devoted to Nanotechnology, including the participation of the ICN2 – VHRI ICREA Prof Victor Puntes and Dr. Jordi Díaz, from the CCiTUB (UB Scientific and Technologica Centers) and member of the Nanoeduca initiative involving ICN2.




ICN2 in the media: The future of biomedicine in Barcelona

ICREA Prof Victor Puntes was interviewed by Xavier Duran about recent advances in biomedicine. The result is an article in the Barcelona Metropolis magazine edited by the Barcelona City Hall. Prof Puntes discusses about how biomedicine and nanoscience have a common future.


First session of the 2015-2016 NanoEduca program held at CCCB

About 90 High School teachers attended the event on July the 7th and they were introduced to the nanoworld. The organizing committee formed by ICN2, UB, UAB and CESIRE explained the different steps of the program and gave some tools and resources to communicate nanoscience. ICREA Prof Victor Puntes gave a talk about the state-of-the art of nanomaterials.



The Associació Ambit B30 organizes with ICN2 a meeting about nanobiosensors

Hospitals and biomedical related initiatives gathered at ICN2 to discuss about the potential of nanotechnology in the field of biomedicine, with a special emphasis on biosensors. The workshop, organised as part of the Biosensors B30 project, explored the opportunities of establishing shared biosensor projects.


ICN2 hosts the second ESCOLAB visit of the season

Once more, a group of students have made their first contact with nanotechnology visiting the ICN2 facilities in a new ESCOLAB visit. They had the opportunity to enter the laboratories of the Inorganic Nanoparticles Group and interacted with the nanoscale through a hands-on experimental session led by the Communication Department.


ICN2 in the media: Prof Victor Puntes collaborates with Diari Ara’s section Ciencia+Art

The Catalan newspaper ARA is releasing a series of conversations between artists and scientists where they explain the similarities of the two disciplines. The talks are presented in online videos and they take place in different environments which have a special relation with what they are talking about. In one of the videos, ICN2 Prof Victor Puntes has a conversation with the magician Sergi Buka and they discuss the connections of nanotechnology and illusionism.


ICN2 in the Media: Nanomedicine and Graphene at Tres14

Tres14 is a science dissemination Program with a long history at the Spanish Television (RTVE, La 2). Yesterday’s Episode was devoted to New Materials, and it includes an extensive interview with ICREA Research professor and ICN2 Group Leader Prof. Victor Puntes.


Nanoparticle technology triples the production of biogas

Developed by researchers from ICN2 and the UAB, it is the first application using nanoparticles to improve the production of this source of renewable energy and the treatment of organic waste. The technology will be commercialised under the newly created spin-off Applied Nanoparticles.





Nanonica announces 2013 Nanotechnology Prize

Technology investment firm Nanonica has announced that in 2013 it will award a Nanotechnology prize in two categories, with cash rewards of €10,000 and €5,000.

The deadline for entries is 20 August 2013.




Gold nanoparticles may enable safer chemotherapy

Publishing in PLOS One, ICREA Research Professor Leader Victor Puntes and colleagues report safe and effective gold-nanoparticle delivery of cisplatin in mouse models of cancer.

Continuing on their previous advances in this project, the team offers detailed information on the safety, efficacy and fate of gold nanoparticle conjugates of cisplatin administered to mice with tumours, including their distribution in and effects on different body tissues.


ICN project among winners of La Marató de TV3 2011

The project, led by ICREA Research Professor and ICN Group Leader Victor Puntes, deals with the use of cerium oxide nanoparticles for treatment of liver maladies

The 2011 edition of La Marató de TV3 raised €8 million for research in Tissue and Organ Regeneration and Transplant, which have just been awarded to 29 research projects led by 56 researchers.



Gold nanoparticles and Cisplatin: a promising new cancer treatment

Nanotargeting and Ferrer sign agreement to develop the treatment, based on the work of ICN Group Leader Victor Puntes and colleagues at other centres.

Delivery of the chemotherapeutic agent Cisplatin to the tumour site by gold nanoparticles prevents many of the side effects that occur with traditional administration.


Gold nanoparticles for removing mercury from polluted water

ICN researchers and colleagues report in ACS Nano a gold nanoparticle-based system to remove mercury(II) from water. The system generates an easily removable and recyclable precipitate.

"Citrate-Coated Gold Nanoparticles As Smart Scavengers for Mercury(II) Removal from Polluted Waters". (Puntes, Ojea-Jiménez, et al., ACS Nano, 2012, 6 (3), 2253–2260)


Carving at the Nanoscale, SCIENCE, 334 (2011)

Researchers at the Catalan Institute of Nanotechnology (ICN) have successfully demonstrated a new method for producing a wide variety of complex hollow nanoparticles. The work has been published in Science.

A common theme in nanoscience research is the recycling of "old" processes and protocols that were once applied crudely on bulk materials in trades and industrial settings, but which can now be applied to nano-sized structures with high precision and resolution using newly available instruments and know-how. After several years of research, scientists of the Catalan Institute of Nanotechnology (ICN), Dr. Edgar Emir Gonzalez (currently at Instituto Geofisico Universidad Javeriana y Universidad Santo Tomas) and ICREA Prof. Victor Puntes in collaboration with ICREA Prof. Jordi Arbiol of the Institute of Materials Science of Barcelona (ICMAB-CSIC), have refined methods based on traditional corrosion techniques (the Kirkendall effect and galvanic, pitting, etching and de-alloying corrosion processes). They show that these methods, which are far more aggressive at the nanoscale than in bulk materials due to the higher surface area of nanostructures, provide interesting pathways for the production of new and exotic materials. By making simple changes in the chemical environment it is possible to tightly control the reaction and diffusion processes at room temperatures, allowing for high yields and high consistency in form and structure. This should make the processes particularly attractive for commercial applications as they are easily adapted to industrial scales. A wide range of structures can be formed, including open boxes, bimetallic and trimetallic double-walled open boxes with pores, multiwalled/multichamber boxes, double-walled, porous and multichamber nanotubes, nanoframes, noble metal fullerenes, and others.


New insights in the life cycle of inorganic nanoparticles, SMALL (2011)

New research results that will lead to improved understandings of the impact of nanomaterials on human health and more effective strategies for detoxification of nanoparticles have recently been published in the journal Small by researchers of ICN and the University of Salzburg.

The reactivity (and potential risks) posed by inorganic nanoparticles in biological environments depends on their physical and chemical state. Biological fluids such as blood, mucus, cell culture media, and others contain a large variety of substances that can interact with and modify nanoparticles. The nanoparticle protein corona, the outcome of the absorption of proteins onto the inorganic surface, is one of the most significant alterations. This coating provides a “biological identity” to nanoparticles in those fluids and determines their interaction with cells, immune systems and other components of biological systems. As a result, detailed knowledge of the nanoparticle protein corona has emerged as a crucial aspect in understanding the biodistribution and reactivity of nanoparticles in organisms and, therefore, for the safe design of the engineered nanoparticles. As reported in Small, Dr. Eudald Casals and ICREA Prof. Victor Puntes of the ICN, along with their colleagues in the University of Salzburg, studied the surface modifications of metal (Au, Ag) and metal oxide (Fe3O4, CeO2 and CoO) nanoparticles with sizes ranging from 7 to 20 nm dispersed in commonly used cell culture medium supplemented with serum. All tested nanoparticles absorb proteins onto their surface, thereby forming a protein corona through a dynamic process evolving towards an irreversible coating (hard protein corona). Despite the fact that the studied nanomaterials have similar characteristics of hydrophobicity and surface charge, different temporal patterns of the protein corona formation were observed that can be considered a fingerprint for nanoparticle identification. Moreover, the researchers found that the protein corona formation on CoO nanoparticles reduces their adverse effects on cellular oxidative stress.


Prof. J. Pascual and Prof. V. Puntes bring Nanotechnology to Punto Radio

On 18th November 2011, Prof. Jordi Pascual, Director of ICN and Prof. Victor Puntes, Inorganic Nanoparticles Group were invited to Punto Radio to talk about nanotechnology and its applications on the program “Luces en la Oscuridad” (Lights in the Darkness) .

The program has been on the air for 21 years and focuses on general humanistic themes. The interview (in Spanish) lasted almost 40 minutes and was about nanotechnology in general, explaining key concepts to the audience in simple terms.


Com Radio - EUREKA

Entrevista amb el Dr. Victor F. Puntes, Investigador Principal del grup Nanoparticules Inorganiques de l'ICN.

"Pots manipular o dissenyar propietats dels materials. Aixo és important...Edat de Pedra, Edat de Bronze, Edat del Silici. Els materials determinen les eines, les eines determinen la civilització."


1st Prize in the 8th National Scientific Photography Contest (FotCiencia) goes to the Inorganic Nanoparticles Group!

"Noche estrellada de Van Gogh (Sterrennacht)" (Van Gogh's Starry Night), wins the first prize in the Micro(scale) Category.

The Inorganic Nanoparticles Group recently submitted three photographs to the 8th National Scientific Fotography Contest (FotCiencia) organised by the Consejo Superior de Investigaciones Cientificas (CSIC) and the Fundación Espanola para la Ciencia y la Tecnologia.