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Monday, 08 October 2012

ICN researchers publish review of paper-based nanobiosensors

ICREA Research Professor Arben Merkoci and doctoral student Claudio Parolo have just published a review of paper-based nanobiosensors for diagnostics, in Chemical Society Reviews

Paper-based nanobiosensors offer great promise to meet the World Health Organisation’s ASSURED guidelines for diagnostics technologies in developing countries.

ICREA Research Professor Arben Merkoci, who leads ICN’s Nanobioelectronics and Biosensors Group, and doctoral student Claudio Parolo have just published a review of paper-based nanobiosensors for diagnostics, in Chemical Society Reviews.In the article, entitled “Paper-based nanobiosensors for diagnostics”, the authors discuss the potential of this technology, comparing the three main classes of paper-based biosensors (dipstick assays, LFAs and mPADs) for their respective detection methods, advantages and disadvantages. They explore detection of proteins, nucleic acids and cells, and discuss specific diagnostic applications of paper-based nanobiosensors with their corresponding biomarkers. The authors hail the great potential of paper-based technologies for diagnostics, including low cost, feasibility, ease of large-scale production, amenability to portability, rapid response, and a high capacity for functionalisation. They cite the importance of these features in the context of the World Health Organisation’s (WHO) APPEND (affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free and deliverable to end-users) guidelines for diagnostics technologies for developing countries.The article “Paper-based nanobiosensors for diagnostics”, can be accessed here.