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-- Monday, 05 September 2022

A DNA-based nanostructure inspired by antibodies as the core of a programmable sensing platform for rapid, single-step diagnostics

A team consisting of current and former members of the ICN2 Nanobioelectronics and Biosensors Group has developed an electrochemical sensor based on a modified DNA scaffold nanostructure able to detect antibodies and proteins in unprocessed biological fluids. It has a Y-shaped architecture that mimics the one of natural Immunoglobulin antibodies. According to the results published in an article in ‘Advanced Functional Materials’, it is selective, specific, and adaptable to the detection of different biomarkers.